Chronic - Persisting for a long time or constantly recurring.
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Peripheral nerves - Any nerve outside the central nervous system.
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Nasal mucosa - The lining of the nasal cavity.
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Bacterium –Any of the single celled organism that commonly multiply by cell division.
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Bacilli - any rod-shaped bacterium
Incubation - The development of an infectious disease from time of the entrance of the pathogen to the appearance of clinical symptoms.
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Antigen - any substance capable of inducing a specific immune response and of reacting with the products of that response.
Antibody - A Y-shaped protein on the surface of B cells that is secreted into the blood or lymph in response to an antigenic stimulus, such as a bacterium, virus, parasite, or transplanted organ, and that neutralizes the antigen by binding specifically to it.
Antibody - A Y-shaped protein on the surface of B cells that is secreted into the blood or lymph in response to an antigenic stimulus, such as a bacterium, virus, parasite, or transplanted organ, and that neutralizes the antigen by binding specifically to it.
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Lymphocytes - Small white blood cells that bear the major responsibility for carrying out the activities of the immune system.
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Macrophages - White blood cells whose job is to destroy invading microorganisms.
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Sensory nerves - Nerves carry that impulses of sensation from the periphery or outward parts of the body to the brain. Sensations include feelings, impressions, and awareness of the state of the body.
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Motor nerves - Nerves that cause movement when stimulated.
Anesthesia - Loss of sensation, usually by damage to a nerve or receptor.
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Lagophalmos - Inability to full close the eyelids.
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Chemical structure of Rifampicin
Rifampicin - An antibacterial and anti-fungal agent used in the treatment of mycobacterium infections, actinomycosis and histoplasmosis.
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Chemical structure of Clofazimine
Clofazimine - An antibacterial effective against Mycobacterium species, including Mycobacterium leprae.
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Chemical structure of Dapsone
Dapsone - An antibacterial drug used primarily to treat leprosy and some forms of dermatitis.
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Lesions - Any pathological or traumatic discontinuity of tissue or loss of function of a part.
Hereditary - Genetically transmitted from parent to offspring.
Clinical -Involving or based on direct observation of the patient
Manifestations - An indication of the existence, reality, or presence of something e.g. A high fever is an early manifestation of the disease.
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Hypogonadism - Diminished hormonal or reproductive functioning in the testes or the ovaries.
Sterility - Incapable of producing offspring.
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Osteoporosis - Porosity and brittleness of the bones due to loss of calcium from the bone matrix.
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Phagocytosis - The engulfing and ingestion of bacteria or other foreign bodies by phagocytes.
Phagocytic - A cell, such as a white blood cell, that engulfs and absorbs waste material, harmful microorganisms, or other foreign bodies in the bloodstream and tissues.
Phagocytic - A cell, such as a white blood cell, that engulfs and absorbs waste material, harmful microorganisms, or other foreign bodies in the bloodstream and tissues.
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Enzymes - Biological substances such as protein that act as catalysts that help complex reactions occur everywhere in life.
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Inflammatory - A localized protective reaction of tissue to irritation, injury, or infection, characterized by pain, redness, swelling, and sometimes loss of function.
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Schwann cells - A cell of the peripheral nervous system that wraps around a nerve fibre, jelly-roll fashion, forming the myelin sheath.
Immunological -The branch of biomedicine concerned with the structure and function of the immune system.